ABSTRACT
Background: Autogenous bone is an ideal material for the reconstruction of hard tissue defects, because it promotes osteogenesis, osteo-induction and osteo-conduction. The use of AutoBT, a novel bone grafting material produced from autogenous teeth, resulted in excellent bone healing based on an analysis of its inorganic components, surface structure and histologic evidence of the healing process.Materials & Methods: Ten sites were included using the following inclusion criteria. Inclusion criteria: One or more sites showing intra-bony defect with probing pocket depth (PPD) ≥ 5mm, clinical attachment loss of ≥ 3mm, 2 or 3 wall intra-bony defects with radiographic defect of size ≥ 3 mm & in same patient mobile teeth indicated for extraction. In test group, among 5 sites, regenerative treatment was performed using tooth as autograft along with chorion membrane & in control group, 5 sites were treated with demineralized freeze-dried bone allograft (DFDBA) with chorion membrane. Clinical parameters such PPD, CAL were evaluated at baseline, 3 & 6 months & radiographic parameters at baseline & after 6 months of treatment.Results: The patients treated by tooth as autoBT material with chorion membrane showed non- significant results to DFDBA with chorion membrane in intra-bony defects in all the clinical parameters. So AutoBT can be used as a useful alternative to DFDBA in periodontal regenerative therapy for intra-bony defects.